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7.8
HIGH CVSS 3.1
CVE-2025-54305
Thermo Fisher Torrent Suite Local Authentication Bypass
Description

An issue was discovered in the Thermo Fisher Torrent Suite Django application 5.18.1. One of the middlewares included in this application, LocalhostAuthMiddleware, authenticates users as ionadmin if the REMOTE_ADDR property in request.META is set to 127.0.0.1, to 127.0.1.1, or to ::1. Any user with local access to the server may bypass authentication.

INFO

Published Date :

Dec. 4, 2025, 3:15 p.m.

Last Modified :

Dec. 16, 2025, 6:50 p.m.

Remotely Exploit :

No

Source :

[email protected]
Affected Products

The following products are affected by CVE-2025-54305 vulnerability. Even if cvefeed.io is aware of the exact versions of the products that are affected, the information is not represented in the table below.

ID Vendor Product Action
1 Thermofisher torrent_suite_software
: Total Affected Vendor : 1 | Products : 1
CVSS Scores
The Common Vulnerability Scoring System is a standardized framework for assessing the severity of vulnerabilities in software and systems. We collect and displays CVSS scores from various sources for each CVE.
Score Version Severity Vector Exploitability Score Impact Score Source
CVSS 3.1 HIGH 134c704f-9b21-4f2e-91b3-4a467353bcc0
Solution
Remove or reconfigure LocalhostAuthMiddleware to prevent unauthenticated access.
  • Remove LocalhostAuthMiddleware if not strictly needed.
  • Reconfigure LocalhostAuthMiddleware for secure settings.
  • Apply vendor patches or updates when available.
References to Advisories, Solutions, and Tools

Here, you will find a curated list of external links that provide in-depth information, practical solutions, and valuable tools related to CVE-2025-54305.

URL Resource
https://assets.thermofisher.com/TFS-Assets/LSG/manuals/MAN0026163-Torrent-Suite-5.18-UG.pdf Product Release Notes
https://documents.thermofisher.com/TFS-Assets/CORP/Product-Guides/Ion_OneTouch_2_and_Torrent_Suite_Software.pdf Vendor Advisory
https://www.thermofisher.com/us/en/home/life-science/sequencing/next-generation-sequencing/ion-torrent-next-generation-sequencing-workflow/ion-torrent-next-generation-sequencing-data-analysis-workflow/ion-torrent-suite-software.html Product
CWE - Common Weakness Enumeration

While CVE identifies specific instances of vulnerabilities, CWE categorizes the common flaws or weaknesses that can lead to vulnerabilities. CVE-2025-54305 is associated with the following CWEs:

Common Attack Pattern Enumeration and Classification (CAPEC)

Common Attack Pattern Enumeration and Classification (CAPEC) stores attack patterns, which are descriptions of the common attributes and approaches employed by adversaries to exploit the CVE-2025-54305 weaknesses.

CAPEC-21: Exploitation of Trusted Identifiers Exploitation of Trusted Identifiers CAPEC-22: Exploiting Trust in Client Exploiting Trust in Client CAPEC-59: Session Credential Falsification through Prediction Session Credential Falsification through Prediction CAPEC-60: Reusing Session IDs (aka Session Replay) Reusing Session IDs (aka Session Replay) CAPEC-94: Adversary in the Middle (AiTM) Adversary in the Middle (AiTM) CAPEC-459: Creating a Rogue Certification Authority Certificate Creating a Rogue Certification Authority Certificate CAPEC-461: Web Services API Signature Forgery Leveraging Hash Function Extension Weakness Web Services API Signature Forgery Leveraging Hash Function Extension Weakness CAPEC-473: Signature Spoof Signature Spoof CAPEC-476: Signature Spoofing by Misrepresentation Signature Spoofing by Misrepresentation CAPEC-667: Bluetooth Impersonation AttackS (BIAS) Bluetooth Impersonation AttackS (BIAS)

We scan GitHub repositories to detect new proof-of-concept exploits. Following list is a collection of public exploits and proof-of-concepts, which have been published on GitHub (sorted by the most recently updated).

Results are limited to the first 15 repositories due to potential performance issues.

The following list is the news that have been mention CVE-2025-54305 vulnerability anywhere in the article.

Results are limited to the first 20 news articles due to potential performance issues.

The following table lists the changes that have been made to the CVE-2025-54305 vulnerability over time.

Vulnerability history details can be useful for understanding the evolution of a vulnerability, and for identifying the most recent changes that may impact the vulnerability's severity, exploitability, or other characteristics.

  • Initial Analysis by [email protected]

    Dec. 16, 2025

    Action Type Old Value New Value
    Added CPE Configuration OR *cpe:2.3:a:thermofisher:torrent_suite_software:5.18.1:*:*:*:*:*:*:*
    Added Reference Type MITRE: https://assets.thermofisher.com/TFS-Assets/LSG/manuals/MAN0026163-Torrent-Suite-5.18-UG.pdf Types: Product, Release Notes
    Added Reference Type MITRE: https://documents.thermofisher.com/TFS-Assets/CORP/Product-Guides/Ion_OneTouch_2_and_Torrent_Suite_Software.pdf Types: Vendor Advisory
    Added Reference Type MITRE: https://www.thermofisher.com/us/en/home/life-science/sequencing/next-generation-sequencing/ion-torrent-next-generation-sequencing-workflow/ion-torrent-next-generation-sequencing-data-analysis-workflow/ion-torrent-suite-software.html Types: Product
  • CVE Modified by 134c704f-9b21-4f2e-91b3-4a467353bcc0

    Dec. 05, 2025

    Action Type Old Value New Value
    Added CVSS V3.1 AV:L/AC:L/PR:L/UI:N/S:U/C:H/I:H/A:H
    Added CWE CWE-290
  • New CVE Received by [email protected]

    Dec. 04, 2025

    Action Type Old Value New Value
    Added Description An issue was discovered in the Thermo Fisher Torrent Suite Django application 5.18.1. One of the middlewares included in this application, LocalhostAuthMiddleware, authenticates users as ionadmin if the REMOTE_ADDR property in request.META is set to 127.0.0.1, to 127.0.1.1, or to ::1. Any user with local access to the server may bypass authentication.
    Added Reference https://assets.thermofisher.com/TFS-Assets/LSG/manuals/MAN0026163-Torrent-Suite-5.18-UG.pdf
    Added Reference https://documents.thermofisher.com/TFS-Assets/CORP/Product-Guides/Ion_OneTouch_2_and_Torrent_Suite_Software.pdf
    Added Reference https://www.thermofisher.com/us/en/home/life-science/sequencing/next-generation-sequencing/ion-torrent-next-generation-sequencing-workflow/ion-torrent-next-generation-sequencing-data-analysis-workflow/ion-torrent-suite-software.html
EPSS is a daily estimate of the probability of exploitation activity being observed over the next 30 days. Following chart shows the EPSS score history of the vulnerability.
Vulnerability Scoring Details
Base CVSS Score: 7.8
Attack Vector
Attack Complexity
Privileges Required
User Interaction
Scope
Confidentiality Impact
Integrity Impact
Availability Impact